A sandbox, but with realistic in-world physics and ability to do anything.
Wanna burner? Boom, take this tin can, make some holes, put in alcohol and burn. Wanna learn how telephone works? Construct it yourself! Game should simulate real-world physics and just store properties of various objects and materials, allowing you to completely unbound from game mechanics and developer's intention. Maybe you'd literally be able to conduct scientific experiments in game, and this would be a great in silico model. Maybe you'd be able to understand how things around you work. Maybe you'd be able to reverse engineer other player's creations. Possibilities are endless, you're having an entire world in your pocket.
...but yeah, we'd barely have enough developers and computer resources for that.