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well if you are talking about actually self-hosting a mail server, then gmail didn't prevent that isp's did.
and downvotes mean nothing since my instance doesn't have them.
It had nothing to do with ISPs. Here's a good writeup on the topic
https://cfenollosa.com/blog/after-self-hosting-my-email-for-twenty-three-years-i-have-thrown-in-the-towel-the-oligopoly-has-won.html