I've used GNU/OpenBSD all the way through community college (US) with minor issues. Biggest issue is having to use platforms like zoom for some online courses, which requires an RTC capable browser (aka firefox or chromium, neither of which I am a big fan of) for the webclient, which the company clearly does not want you using as they won't actually give a prompt to use the webclient until you click their link to fail opening their native spyware client (so who knows when the webclient will just disappear altogether). Another issue was professors using proprietary microsoft formats which require installing libreoffice, which isn't tooling I particularly enjoy using, but at least the option is there. I haven't had to use a malware "lockdown" browser or anything like that thankfully (though if I had to, I'd just use computers on-campus to do the work). Most classes allow submissions in PDF, and if the syllabus only allows docx submissions, the professor will allow me to submit PDF after contacting them.