Adjustment means they can make exceptions if your disability requires it. The job requirement part depends on the reasons, eg if being present is an inherent part of the job, (it would be impossible to be a hairdresser via zoom), then the adjustment can be refused. But if it’s only for social reasons, there may be some flexibility. You don’t know until you ask! It’s also possible that the employer can make the adjustment at the workplace. For example if a person can’t use stairs, and building doesn’t have a lift, then make sure they are situated only on ground floor and all meetings are held in accessible rooms etc. I know it’s not always easy to approach employer and some of them might be dismissive of requests. But… if it’s a choice between suffer and maybe have to quit work, or ask and possibly get some accomodations there’s no harm at all in asking.