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this post was submitted on 13 Dec 2024
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Mirror molecules that by themselves could easily pose a risk to anyone exposed by them.
My point in even mentioning Thalidomide was that we already know what mirroring even a simple compound can do to living things, nevermind complex proteins and entire organisms.
GMOs can be dangerous as is without proper safeguards, but at least in most instances it's only the living organism itself that's dangerous. With mirroring, any part of that organism could be dangerous to normal lifeforms, so even sterilised mirror waste could be dangerous
It's worth bearing in mind that opposite chirality is not inherently dangerous. Whether an individual mirror molecule poses a problem depends on the specific biochemical context. While there have been famous situations where a chiral enantiomer proved toxic, for every one of these there's been plenty more instances where biology shrugs and doesn't gaf.
Does this mean we shouldn't worry? Obviously not, but it just means we should do more to manage the general risks of molecular engineering for microbes. Chirality is only one of many, many routes through which risks can come, so there's no point fixating on that.