It's possible to win a round without producing any. You might get some as a random drop. Alcohol and it's production buildings will also pop up as a takable option and by not taking it ever the game will be harder. Meaning the game will punish you by being harder for ignoring it. You can also forbid your colonists from drinking it except in some very rare scenarios where you could just abandon a run/town. So basically you can avoid it but it's always gonna be in your face. Feel free to ask if you want more info :)