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For this I usually go with 27. Trade slightly more cortex development while only losing about 3% more of my collagen. So like one crowfoot and a forehead crease, but no more. Eyes are also stable enough for eye surgery but not going into retinal decline like in the 30s. Basically your late 20s rides off all your physical generation for a lot of different soft tissues being peak into ~25 but not having caused the damage that starts to build up and cause side effects in your 30s.
Are we min/maxing our answers? Lol